Experimentell karakterisering av den humana icke-sekvensspecifika
Livsstilsövergångar i växtpatogena colletotrichum-svampar
The N- and C-terminal coiled-coil domains of nCLU interacted with each other, suggesting that the protein could dimerize or fold. PLA0263 Sigma-Aldrich Rabbit anti-Ku70 Antibody, Affinity Purified Powered by Bethyl Laboratories, Inc. Synonym: 5′-dRP lyase Ku70, 5′-deoxyribose-5-phosphate lyase Ku70, 70 kDa subunit of Ku antigen, 70 kDa subunit, 70kDa, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, ATP-dependent DNA helicase II, CTC box binding factor 75 kDa subunit, CTC box Mar 5, 2021 KU70; TLAA; ML8; ATP-Dependent DNA Helicase II, 70 KDa Subunit by UniProt/SwissProt and Phenotype-based relationships between UniProt accession no. P12956. Description.
KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. UniProt Consortium European Bioinformatics Institute Protein Information Resource SIB Swiss Institute of Bioinformatics. UniProt is an ELIXIR core data resource. 2001-03-01 KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance.
Proteomics studie av exkutomer från blodkroppsretikulocyter
The dimer associates in a DNA-dependent manner with PRKDC to form the DNA-dependent protein kinase complex DNA-PK, and with the LIG4-XRCC4 complex to form the core of the non-homologous end joining (NHEJ) complex. Additional components of the NHEJ complex include NHEJ1/XLF and PAXX. The Ku70 and Ku80 proteins consist of three structural domains. The N-terminal domain is an alpha/beta domain.
Proteomics studie av exkutomer från blodkroppsretikulocyter
Supplied as 100 µg purified antibody (1 mg/mL). Rad1/Rad9/Hus1/Rad17 and Ku70 are two additional epistasis groups, which act in the Rad3/Rad26 pathway. However, Rad3/Rad26 must have additional target(s), as cells lacking Tel1/Rad32, Rad1/Rad9/Hus1/Rad17, and Ku70 groups did not circularize chromosomes. Ku70 binding activity was localized to the C-terminal coiled-coil domain of nCLU.
Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications. This antibody reacts with Human, Mouse samples. Supplied as 100 µg purified antibody (1 mg/mL). Rad1/Rad9/Hus1/Rad17 and Ku70 are two additional epistasis groups, which act in the Rad3/Rad26 pathway. However, Rad3/Rad26 must have additional target(s), as cells lacking Tel1/Rad32, Rad1/Rad9/Hus1/Rad17, and Ku70 groups did not circularize chromosomes. Ku70 binding activity was localized to the C-terminal coiled-coil domain of nCLU.
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Uniprot No. P12956. Target Names, XRCC6.
Lane 5: HELA Whole Cell Lysate at 40ug. Lane 6: A431 Whole Cell Lysate at 40ug. Ku70 is the 70 kDa subunit of the lupus Ku autoantigen.
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Experimentell karakterisering av den humana icke-sekvensspecifika
Tested in Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC) and Immunohistochemistry (IHC) applications. This antibody reacts with Human, Mouse samples. … Interestingly, Ku70 and Ku 86 negatively regulate the transcriptional activity of ESE-1. Using a series of deletion constructs, we have determined that the Ku proteins bind to the DNA-binding domain of ESE-1.